| Venerdì 21 gennaio 2011 | |||
| 20.45 | Southend United | – | Bury |
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| Sabato 22 gennaio 2011 | |||
| 16.00 | Accrington Stanley | – | Hereford United |
| 16.00 | Aldershot Town | – | Crewe Alexandra |
| 16.00 | Bradford City | – | Burton Albion |
| 16.00 | Macclesfield Town | – | Barnet |
| 16.00 | Northampton Town | – | Oxford United |
| 16.00 | Port Vale | – | Cheltenham Town |
| 16.00 | Shrewsbury Town | – | Chesterfield |
| 16.00 | Stevenage | – | Morecambe |
| 16.00 | Stockport County | – | Lincoln City |
| 16.00 | Torquay United | – | Gillingham |
| 16.00 | Wycombe Wanderers | – | Rotherham United |