Sabato 22 gennaio 2011
| 16.00 | Peterborough United | – | Hartlepool United |
| 16.00 | Bristol Rovers | – | Swindon Town |
| 16.00 | Yeovil Town | – | Rochdale |
| 16.00 | Tranmere Rovers | – | Southampton |
| 16.00 | AFC Bournemouth | – | Brighton and Hove Albion |
| 16.00 | Oldham Athletic | – | Brentford |
| 16.00 | Notts County | – | Carlisle United |
| 16.00 | Leyton Orient | – | Sheffield Wednesday |
| 16.00 | Huddersfield Town | – | Colchester United |
| 16.00 | Exeter City | – | Walsall |
| 16.00 | Dagenham and Redbridge | – | Milton Keynes Dons |
| 16.00 | Charlton Athletic | – | Plymouth Argyle |